PhD, Osaka University, Japan
Office: Biology 2204B
Phone: (912) 478-4731
General Biology, Microbiology, Principles of Biology I Lab
My research interests center on using molecular techniques to improve the supply of precursors for bio-based products. Examples include using protein and metabolic engineering techniques to generate recombinant bacterial strains to enhance production of polyhydroxyalkanoate (PHA) biodegradable polymers from renewable resources such as sugars and plant oils. Current and previous studies have used rational design of fatty acid biosynthetic enzymes based on x-ray crystal structures to alter their substrate specificity to provide monomers for PHA biosynthesis. One of my future plans is to work on the molecular enzymology of the enzymes involved in the biosynthesis of these polymers, i.e. the phaC gene encoding the PHA synthase enzyme involved in the synthesis of the polymer and the phaR gene encoding a protein subunit essential for the activity of the PHA synthase as well as to characterize of these enzymes which have been successfully over-expressed. The ultimate aim is to understand the mechanism of action of the enzyme biopolymer under appropriate conditions.
Last updated: 1/27/2021